Graves Disease in Infancy

Anticardiolipin Antibodies and Immunoglobulin M and A in Graves’ Disease

Background: Graves’ disease is an autoimmune disease, characterized by the presence of antibodies directed to TSH receptor or nearby regions as well as antibodies to double strands DNA (dsDNA) anticardiolipin and nuclear antibodies. This study evaluated anticardiolipin and rheumatoid factor, such as IgA and IgM antibodies in patients with Graves’ disease. Patients and methods: Anticardiolipin a...

[Graves' disease].

inflammatory bowel disease in infancy

background inflammatory bowel disease (ibd) may begin as early as the first year of life. the objective of the present study was to determine the characteristics and clinical course of children with early-onset ibd. materials and methods the records of patients with ibd admitted to children medical center hospital during 2003-2006 were screened for those with disease onset before the first year...

Microchimerism in Graves' Disease

Microchimerism is the presence of cells from one individual in another genetically distinct individual. Pregnancy is the main cause of natural microchimerism through transplacental bidirectional cell trafficking between mother and fetus. The consequences of pregnancy-related microchimerism are under active investigation. However, many authors have suggested a close relationship linking fetal mi...

Graves' Disease.

Graves’ disease was first recognized in the 19th century as a syndrome comprising an enlarged and overactive thyroid gland, an accelerated heart rate, and ocular abnormalities (Fig. 1). Critical for our current understanding of this disease was the discovery of its autoimmune basis, which results from complex interactions between genetic and environmental factors.1,2 Graves’ disease has adverse...